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Fluorescein, 1,1'-dioctadecyl-3,3,3',3'-tetramethylindocarbocyanine perchlorate (DiI), and DiI-labeled RNA were loaded in three distinct microchannels, respectively. In the presence of target DNA or RNA, the number of fluorescently labeled targets formed complexes with Au NPs and displayed fluorescence. The limit of detection of the DNA assay (0.01 pM) was approximately one-tenth of that of the conventional duplex DNA hybridization assay and the RNA assay (2 pM) was comparable to the colorimetric real-time RT-PCR assay. The device developed in this study is a useful tool for sensitive, selective, and simultaneous detection of DNA and RNA targets.Viewing Item 4 of 7\n\nWednesday, June 24, 2003\n\nWednesday, June 24, 2003\n\nYou can direct traffic from any corner of any direction. If you come to a dead end with no way in or out. 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